Dr. Natalie Gentile is a board-certified Family Medicine and Lifestyle Medicine physician serving patients through the direct primary care (DPC) model. 

In 2019 she founded her DPC practice, Gentile Family Direct Primary Care, in Pittsburgh. In 2022 she co-founded Direct Care Physicians of Pittsburgh, a physician-led management services organization supporting independently owned DPC practices across the region. And in 2023, she founded Rebel Wellness, Pittsburgh’s only woman physician-owned lifestyle medicine studio.

Trained at the University of Pittsburgh School of Medicine and Mayo Clinic, Dr. Gentile’s work is grounded in evidence-based medicine, continuity of care, and the belief that primary care should be accessible, relationship-centered, and free from unnecessary bureaucracy. After practicing in large academic systems, she returned to her hometown of Pittsburgh to build a practice model that prioritizes time, trust, and whole-person health.

Dr. Gentile integrates lifestyle medicine principles into clinical care without moralizing health or weight, and she is outspoken about the structural barriers that limit patient outcomes and physician sustainability.

Follow Dr. G on social media via @nataliegentilemd on Instagram, Substack and on Facebook.